Complications associated with Diabetes

The term diabetes mellitus describes several diseases of abnormal carbohydrate metabolism that are characterized by hyperglycaemia. It is associated with a relative or absolute impairment in insulin secretion, along with varying degrees of peripheral resistance to the action of insulin. They are derived after doing many clinical trials on animal models. Every few years, the diabetes community revaluates the current recommendations for the classification, diagnosis, and screening of diabetes, reflecting new information from research and clinical practice which in turns help in understanding current prevention and treatment options and cost effectiveness in treatment and prevention of Diabetes. People with type1 and type2 diabetes have an increased risk of developing a number of serious health problems. Consistently high blood glucose levels can lead to serious diseases affecting the Macro vascular and micro vascular complications. In addition, people with diabetes also have a higher risk of developing infections. In almost all high-income countries, diabetes is a leading cause of cardiovascular disease, blindness, kidney failure, and lower limb amputation. Maintaining blood glucose levels, blood pressure, and cholesterol at or close to normal can help delay or prevent diabetes complications. Hypoglycaemia and Hyperglycaemia are the other two factors are the two major complications of diabetes where hyperglycaemia is an acute complication sharing many symptoms and hypoglycaemia is an acute complication of several diabetes treatments. Glycosylated haemoglobin is a form of haemoglobin that is measured primarily to identify the average plasma glucose concentration over prolonged periods of time.

  • Type 2 diabetes -Complications and treatment
  • Microvascular complications: Retinopathy, neuropathy, and nephropathy
  • Macrovascular complications: Coronary artery diseases, cardiomyopathy, and stroke
  • Hypoglycemia, Hyperglycemia and glycosylated haemoglobin
  • Latent autoimmune diabetes of adults (LADA)
  • Hypertension
  • Embryonic stem cell therapy for diabetes and its complications
  • Preclinical safety evaluation of stem cell-based therapies for diabetes
  • Nephrogenic Diabetes Insipidus

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