Obesity and Metabolism for Diabetes

Obesity significantly increases the risk of type 2 diabetes by disrupting metabolic processes such as insulin signaling and lipid metabolism. Excess fat, particularly visceral fat, promotes chronic inflammation and insulin resistance. Metabolic syndrome—a cluster of conditions including obesity, high blood pressure, and dyslipidemia—further heightens diabetes risk. Weight loss through diet, physical activity, and behavioral therapy improves insulin sensitivity and glycemic control. Pharmacological and surgical interventions like GLP-1 agonists and bariatric surgery offer additional options. Understanding the link between obesity and metabolic dysfunction is essential in preventing and managing diabetes. Targeting metabolic health is a core strategy in diabetes care.

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